Resveratrol attenuates oxidative stress in chronic obstructive pulmonary disease by Nrf2-mediated inhibition of ferroptosis.
BACKGROUND Oxidative stress and ferroptosis contribute to cigarette smoke (CS)-related epithelial injury in chronic obstructive pulmonary disease (COPD), but the extent to which resveratrol (RES) modulates this process through Nrf2 remains incompletely defined. METHODS We used a CS plus lipopolysaccharide-induced mou...