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Author

Wen-Ze Huang

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Open access Sep 2026

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

It is demonstrated that SF3B1 undergoes intrinsic, IDR‐driven liquid‐liquid phase separation both in vitro and in vivo, forming nuclear condensates in oocytes and early embryos, which is essential for successful development to the blastocyst stage.

Kang Zhao, Ting-Yu Han, Yan-Li Cheng et al. · 0 citations
Open access Jul 2026

Spaceflight multi-omics reveals vulnerabilities of human germ cell development

An automated bioreactor was utilized that supported long-term differentiation of human embryonic stem cells into human induced primordial germ cells, human induced ovarian follicles, and human induced spermatogonial stem cells aboard spacecraft and demonstrated preserved genomic integrity despite these functional pertu...

Ying Li, Hui Gao, Jie Xiong et al. · 0 citations

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