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Author

Wen-Zhi Li

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Open access Oct 2026

Single-cell transcriptomic and immune microenvironment analyses reveal a TIMP1-associated OLFM4⁺ tumor epithelial program linked to colorectal cancer progression and immune evasion.

C3 OLFM4⁺ cells represent a stem-like, metabolically active tumor epithelial state associated with CRC progression, fibroblast-derived WNT signaling, immune-evasion-related features, and unfavorable prognosis.

Rui Leng, Xian-Ding Cui, Xin-Yu Wu et al. · 0 citations

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