Author

Wenbin Dong

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Oct 2026

A comprehensive single-cell transcriptomic atlas of hippocampal microglia in a mouse model of traumatic brain injury.

BACKGROUND Traumatic brain injury (TBI) triggers microglial activation and disrupts the inflammatory microenvironment in the hippocampus, which are key contributors to neuroinflammation and subsequent secondary brain damage. Nevertheless, the cellular heterogeneity of microglia, their pro-inflammatory activation mechan...

Wen-Bin Dong, Yi-Nuo Jia, Rui-Lin Wang et al. · Brain Research · 0 citations

Review Aug 2026

Evolution of CRISPR-cas detection systems: From nucleic acid recognition to omnidirectional point-of-care diagnostic applications.

This review systematically summarizes the core molecular mechanisms of CRISPR-Cas detection platforms and presents the applications of this technology in fields such as infectious disease surveillance, cancer liquid biopsy, preliminary screening of genetic diseases, food and environmental safety, and veterinary port qu...

Rui-Lin Wang, Wei Pang, Mingxuan Yu et al. · Diagnostic microbiology and... · 1 citation