Jul 2026
Gram-scale production of forskolin in yeast through biosynthetic network elucidation and pathway optimization.
This study reconstructed an efficient biosynthetic pathway of forskolin in yeast and subsequently optimized its production efficiency through multidimensional engineering strategies including central carbon flux optimization, rate-limiting enzyme engineering, P450 electron transfer chain reinforcement, and fermentation...
Meiling Jiang, Hao Tang, Ying Ma et al.
· Bioresource Technology · 0 citations