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Author

Wenguang Liu

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Review Oct 2026

α-Lipoic acid: from a mitochondrial cofactor to a versatile platform for dynamic biomaterials and translational biomedicine.

α-Lipoic acid (LA) is a naturally occurring small molecule possessing both endogenous cofactor activity and dynamic covalent polymerization capability. The 1,2-dithiolane ring in its structure enables both redox-responsive biological functions and ring-opening polymerization to yield polylipoic acid (PolyLA) with a dyn...

Chun-Yan Cui, Chen-Xi Zheng, Zhen Liu et al. · 0 citations
Aug 2026

Natural Bone Regeneration-Inspired Poly(Lipoic Acid)-Based Organic-Inorganic Bone Adhesive for Osteoporotic Bone Defect Repair.

Osteoporosis, featured by imbalanced bone remodeling, faces clinical challenges including microenvironment dysregulation, insufficient mineralization, and poor material fixation. Inspired by natural bone regeneration-where ossification centers and surrounding soft tissues orchestrate mineralization and tissue integrati...

Lin-Bo Wei, Ziyi Xu, Zi-Hui Yu et al. · 0 citations
Aug 2026

Nanomedicine for epilepsy: Expanding beyond conventional drug targets.

This discussion aims to inspire a reorientation of nanomedicine strategies toward precision therapy for epilepsy by highlighting how emerging nanomedicines are expanding the therapeutic target repertoire to include key non-neuronal nodes, with a focus on neuroinflammation and BBB repair.

Yage Sun, Wenguang Liu · 0 citations

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