Diabetic infected wounds remain difficult to heal because bacterial colonization, biofilm formation, excessive reactive oxygen species (ROS), and persistent inflammation mutually reinforce one another in the diabetic wound microenvironment. In diabetic wounds, the temporal immune switch is often impaired, resulting in...
Jian Zhang, Yan Lin, Yan Liu et al.· Biomaterials Research· 0 citations
Traditional cancer treatment methods, such as chemotherapy, radiotherapy, and immunotherapy, are often limited by poor treatment efficacy, poor targeting, and adverse side effects, as well as intrinsic or acquired drug resistance, which are mainly caused by the complex and immunosuppressive tumor microenvironment. The...