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Wesam Bassiouni

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Open access Aug 2026

Restoring neurovascular coupling in Alzheimer’s disease tauopathy through M1 mAChR modulation

It is demonstrated that M1 mAChR positive allosteric modulation reverses tau-induced neurovascular dysfunction, supporting M1 mAChR activation as a promising disease-modifying approach for Alzheimer’s disease and suggesting that therapeutic efficacy is influenced by biological sex.

Wesam Bassiouni, Mohamed Abdelnaby, En-Hung Ai et al. · 0 citations

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