Author

Wibisono Hasanul Muhtaram

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Review Open access Sep 2026

Pathophysiology, Clinical Manifestations, and Pharmacological Management of Pruritus in Primary Biliary Cholangitis: A Systematic Review

Treatments that target bile acid metabolism, the ATX-LPA pathway, pruritogenic cytokines, and the opioid system have shown potential to reduce pruritus intensity and improve quality of life for patients.

Retno Dwi Utami, Nensy Dwi Astika, Made Prajnana Adhi Parasikan Susana et al. · Research of Service Administ... · 0 citations

Insulin Enhances NF-κB Activation in Luminal A T -47D Breast Cancer Cells Exposed to Low-Dose Doxorubicin

Findings indicate that insulin increases NF-κB activation in doxorubicin -treated T-47D breast cancer cells and may sustain NF-κB activity against the cytotoxic effects of doxorubicin.

Wibisono Hasanul Muhtaram, Novrita Padauleng, Rizka Vidya Lestari et al. · 0 citations

Open access Jul 2026

Insulin-Induced NF-κB Activation May Contribute to Doxorubicin Resistance in Luminal A T-47D Breast Cancer Cells

Findings indicate that insulin increases NF-κB activation in doxorubicin-treated T-47D breast cancer cells and may sustain NF-κB activity against the cytotoxic effects of doxorubicin.

Wibisono Hasanul Muhtaram, Novrita Padauleng, Rizka Vidya Lestari · Lombok Medical Journal · 0 citations