Molnupiravir, first small molecule therapeutic to demonstrate therapeutic efficacy against Venezuelan equine encephalitis virus in the cynomolgus macaque model.
Venezuelan equine encephalitis virus (VEEV) is an emergent arbovirus of major epidemic concern. Associated with periodic outbreaks in Central and South America, VEEV has a high morbidity rate in humans due to a 1:1 clinical-to-subclinical ratio and can cause neurological disease in up to 14% of cases. Concerningly, no...