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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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William J. Gibson

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Open access Sep 2026

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

ABSTRACT Chemical‐induced proximity, particularly via molecular glues, represents a rapidly advancing therapeutic paradigm. Expanding the scope of proximity‐based therapeutics requires generalizable discovery platforms that can be easily tailored to diverse presenter proteins. Here, we report a versatile DNA‐encoded li...

Bing-Qi Tong, Sunny A. Tang, Yi-Fan Deng et al. · 0 citations
Aug 2026

Interpretable Prediction of Ligand-Protein Binding without Protein Structural Information.

Ligand-protein binding prediction remains a central challenge, yet the contribution of ligand-side information to performance is unclear and ligand-only models as interpretable screening tools are established and used as a baseline for assessing the added value of protein representations.

Ananthan Sadagopan, Anurag Sodhi, William J. Gibson · 0 citations

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