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William Yun

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Open access Aug 2026

Pathological hippocampal-cortical hypersynchronization disrupts memory in temporal lobe epilepsy: A multimodal intracranial electroencephalographic-functional magnetic resonance imaging study.

The multimodal findings suggest that increased hippocampal connectivity in the epileptogenic hemisphere may reflect pathological hypersynchronization that disrupts efficient memory network coordination in TLE and highlight hippocampal connectivity as a promising candidate biomarker for characterizing individual memory outcomes.

Ruxue Gong, Xiaolong Peng, Rebecca W. Roth et al. · 0 citations

Prediction of Long-Term Postsurgical Seizure Recurrence From MRI Brain Hub Disruption in Patients With Temporal Lobe Epilepsy.

The model achieved high specificity in predicting long-term seizure recurrence, which supports its potential clinical utility for postoperative risk stratification and counseling rather than surgical exclusion and underscores the translational potential of network-level biomarkers to complement conventional predictors.

V.Yu. Karpychev, Rebecca W. Roth, William Yun et al. · 0 citations