Open access
Aug 2026
Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States
ABSTRACT Cells must preserve and rewrite transcriptional memory to maintain identity and adapt to stress, yet the physical mechanisms governing this process remain unclear. Recent work implicates genome geometry in encoding transcriptional memory, with nanoscopic chromatin packing domains (PDs) serving as structural un...
Cody L. Dunton, Carrillo Paola Gonzalez, L. Almassalha et al.
· Advancement of science · 0 citations