Open access
Sep 2026
Zfp469 Deletion Attenuates Liver Fibrosis by Suppressing Extracellular Matrix Production in Hepatic Stellate Cells.
BACKGROUND Liver fibrosis is driven by excessive extracellular matrix (ECM) deposition following chronic injury. Mutations in the human zinc finger protein 469 (ZNF469) cause Brittle Cornea Syndrome, a systemic connective tissue disorder, yet its functional role in hepatic fibrogenesis remains unexplored in vivo. This...
Nantawat Satthawiwat, Archittapon Nokkeaw, Bootsakorn Boonkaew et al.
· Biomedical Journal · 0 citations