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Wu-Can Zhang

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Review Open access Sep 2026

Restoring NAD+ pathways in brain aging and neurodegenerative diseases: roles of vitamin B3 metabolites, gut microbiota, and exercise in cognitive health

Aging and neurodegenerative disorders (NDDs) are intricately linked to a gradual deterioration in nicotinamide adenine dinucleotide (NAD+) metabolism, compromised mitochondrial functionality, persistent inflammation, and modified gut–brain interactions. Derivatives of vitamin B3, such as niacin, nicotinamide, nicotinam...

Wu-Can Zhang · 0 citations

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