Review
Open access
Jul 2026
Association of rs3736228 polymorphism in LRP5 gene with bone fracture and osteoporosis: a systematic review and updated meta-analysis
A subgroup analysis to explore the source of heterogeneity according to gender, race, disease, genotyping methods, control resources, female menopause, and HWE balance revealed a significant association between rs3736228 polymorphism and an increased risk of osteoporosis and fractures.
Chi Zhang, Wu-Hua Liu, Youhua Wang et al.
· BMC Musculoskeletal Disorder... · 0 citations