Open access
Sep 2026
SAMSN1 restricts Japanese encephalitis virus replication by recruiting TRIM21 to degrade viral proteins and activate the interferon pathway
Japanese encephalitis virus (JEV), a zoonotic mosquito-transmitted flavivirus, induces human encephalitis and swine reproductive diseases. No antiviral drugs or treatments exist for flavivirus infections, which cause severe symptoms. Even though some host proteins can suppress flavivirus proliferation, the virus can in...
Chen Wang, Wen-Zhen Qin, Xing-Ya Wang et al.
· Veterinary Research · 0 citations