Author

X. Houard

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Review Open access Aug 2026

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

Calcium phosphate biomineralization is a highly regulated process that underlies the formation of vertebrate mineralized tissues. While proteins have long been recognized as the principal regulators of mineral formation, accumulating experimental evidence suggests that nucleic acids may also contribute to this process...

Fanny Duhalde, J. Landoulsi, X. Houard · The FASEB Journal · 0 citations

Open access Aug 2026

EXTL3 dysfunction identified as a driver of aberrant bone development in severe familial ankylosing spondylitis.

This study identifies EXTL3 as a genetic modifier of structural severity in AS and reveals a previously unrecognised role for HS metabolism in pathological ossification, which supports a model in which HLA-B27 primarily confers disease susceptibility, whereas rare variants such as EXTL3 contribute to structural progres...

S. Hilliquin, Olivier Fogel, Mathilde Tissier et al. · Annals of the Rheumatic Dise... · 0 citations