Author

Xingxiang Pu

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Open access Sep 2026

Precision medicine of rare tumors: Uncovering the potential actionable targets through genomic profiling

Rare tumors constitute a substantial portion of cancer diagnoses, however, research remains limited. To assess the utility of genomic testing for informing treatment decisions, we retrospectively evaluated the landscape of actionable genomic alterations and immune biomarkers in rare tumors. Genomic and clinical data fr...

Guo-Min Lin, Yue Hao, Qian Wang et al. · International Open Medical J... · 0 citations

Review Open access Jul 2026

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

The current developments in engineering of Cas effector protein, optimizing guide RNA designs, developing advanced reporter probes, and utilizing chemical additives are summarized and their significant contribution to increasing the fidelity of editing and diagnostic sensitivity is highlighted.

Sheng Li, Han Li, Bojie Chen et al. · Interdisciplinary Medicine · 1 citation