Author

X. Qiu

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Open access Sep 2026

A recombinant Newcastle disease virus-vectored multi-epitope vaccine confers protection against QX-like infectious bronchitis virus in chickens

Protection was accompanied by an increased frequency of splenic CD3 + CD8 + T cells, particularly after booster immunization, suggesting a role for cellular immunity alongside neutralizing antibodies.

Fei Wang, Jia-Nan Xie, Guo-Yuan Wen et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

The K247 ubiquitination site of the Newcastle disease virus M protein enhances viral budding to facilitate rapid exploitation of host cell sphingolipid metabolites

Using recombinant viruses generated in this study, the effects of the K247 ubiquitination site on host cell metabolism are investigated and indicate that the K247 residue of the NDV M protein enhances viral budding and promotes rapid utilization of host sphingolipids.

Jun Dai, Fan-Xin Liu, Yiyi Feng et al. · Poultry Science · 0 citations

Open access Jul 2026

Coronavirus papain-like protease antagonizes innate immunity by cleaving Importin α1 to disrupt nuclear transport

The PLpro-TM protein is identified as a pan-coronavirus antagonist of nucleocytoplasmic trafficking and innate immune response and established PLpro-TM-mediated cleavage of Importin α1 as a conserved immune evasion strategy across coronaviruses and highlights this interaction as a potential target for broad-spectrum an...

Jie-Huang Wang, Wenxiang Xue, Ying-Jie Sun et al. · bioRxiv · 0 citations