Noninvasive prediction of functional coronary stenosis and multivessel disease in acute coronary syndrome using integrated lipidomics and machine learning
While invasive angiography and quantitative flow ratio (QFR) are gold standards for diagnosing coronary functional ischemia, they primarily reflect focal anatomical hemodynamics and fail to capture the systemic metabolic vulnerability of the patient. We aimed to develop and rigorously validate a noninvasive predi...