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Xandramela Limala Alicya Junaidi Lee

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Open access Aug 2026

Characterization of Hesperidin-PEG 1000 Solid Dispersion Prepared by Freeze Drying Method

Hesperidin is a disaccharide-derivative bioflavonoid in BCS class II, insoluble in water but soluble in propylene glycol and polyethylene glycol, and its poor aqueous solubility may impair bioavailability, necessitating modification via solid dispersion. In this study, a hesperidin–PEG 1000 system was prepared at 1:1 a...

Aga Mikail, A. T. Pradana, E. Fitriani et al. · 0 citations

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