Xi Chen

Establishment of an ex vivo vascular tissue model to investigate bunyavirus-triggered vascular endothelial injury

ABSTRACT Severe fever with thrombocytopenia syndrome, an emerging infectious disease caused by the tick-borne bunyavirus severe fever with thrombocytopenia syndrome virus (SFTSV), is associated with a high clinical fatality rate of 12%–50%. Vascular endothelial injury triggered by SFTSV infection has been linked to sev...