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Review Jul 2026

Immune cell metabolic reprogramming mediates ICI therapy resistance.

This review systematically delineates the metabolic reprogramming features of immune cells in the TME, dissects the molecular mechanisms governing ICI resistance, and summarizes combination strategies targeting metabolic pathways to reverse resistance, providing theoretical and translational insights for optimizing can...

Zhi Xu, Kequan Xu, Yi Ju et al. · 0 citations

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