Author

Xi-Feng Li

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Sep 2026

A Brain-Targeted Nanozyme System for Alleviating Poststroke Neuroinflammation via Synergistic Antioxidant and Anti-inflammatory Mechanisms.

Ischemic stroke (IS) is severely aggravated by oxidative stress and neuroinflammation, while the blood-brain barrier (BBB) poses a major obstacle to effective therapy. Herein, we developed a brain-targeted nanozyme system (TLNP@Pt/Fe3O4) by encapsulating Pt/Fe3O4 nanozymes into T7 peptide-modified lipid nanoparticles....

Bo-Yang Wei, Yu Wu, Jia-Ming Zhou et al. · ACS Applied Materials and In... · 0 citations

Sep 2026

Genetic Determinants of Vascular Dementia: Blood Metabolite Associations and Candidate Therapeutic Target Prioritization.

Vascular dementia (VaD), caused by reduced cerebral blood flow, is a common form of dementia lacking effective treatments. This study used genome-wide association study (GWAS) summary data, Mendelian randomization (MR), and colocalization analyzes to prioritize blood metabolites and candidate therapeutic targets associ...

Cheng-Wei Chen, Xiang Zou, Jie Hu et al. · Genetic Epidemiology · 0 citations

Jul 2026

Development and validation of the FLATS score to predict periprocedural ischemic events after stent-assisted coiling for ruptured intracranial aneurysms in the acute phase: a nationwide chinese registry

The FLATS score is an easily applicable aid for risk stratification of IEs after SAC for acute aSAH, and is an easily applicable aid for risk stratification of IEs after SAC for acute aSAH.

Chi Huang, Hailong Zhong, Yi-Ming Bi et al. · Neurosurgical review · 0 citations