Sep 2026
Design, synthesis, and screening of novel thienopyrimidine derivatives as PI3K/HDAC dual inhibitors against cervical cancer cells.
Although rapid systemic clearance currently limits its in vivo application, the potent cellular efficacy of B7 highlights its utility as a dual PI3K/HDAC lead compound, providing a distinct chemical scaffold for further structural optimization.
Wei-Xu Wang, Naziyila Shayilan, Xi-Jin Qi et al.
· European journal of medicina... · 0 citations