Author

Xiliang Luo

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Aug 2026

Self-Assembled Peptide Hydrogel-Engineered Au/SCN/PCN-222 Photocathode for Antifouling Photoelectrochemical Immunoassay of S100B.

S100B is a clinically important biomarker for traumatic brain injury and neurodegenerative diseases, necessitating the development of sensitive and reliable analytical methods for its determination in complex biological fluids susceptible to potential biofouling and electroactive interference. Herein, we report a robus...

Feng Xu, Yao-Yao Xiao, Gao-Chao Fan et al. · Analytical Chemistry · 0 citations

Aug 2026

Engineering a Disulfide-Directed Hairpin-Shaped Antifouling Peptide for Reliable Electrochemical Detection of CA15-3 in Human Serum.

The precise detection of biomarkers in complex biofluids remains a significant challenge for electrochemical biosensors, largely due to the nonspecific adsorption of proteins and other molecules. While zwitterionic peptides offer excellent antifouling properties, their typical linear architectures are prone to protease...

Shuyu Jiang, Shi-Cheng Liu, Zhen Song et al. · Analytical Chemistry · 0 citations

Aug 2026

A Multifunctional Lasso-like Peptide-Based Electrochemical Biosensor: Overcoming Biofouling and Enzymatic Degradation for High-Fidelity Immunoglobulin G Assay.

The reliable electrochemical detection of immunoglobulin G (IgG) in complex biological fluids is severely hampered by nonspecific protein fouling and enzymatic degradation. Inspired by natural lasso peptides, we engineer a multifunctional lasso-like peptide (LaP) composed entirely of D-amino acids that uniquely integra...

Yanlong Huang, Jia-Wei Pan, Jingwen Xu et al. · Analytical Chemistry · 0 citations