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Author

Xi-Meng Zhang

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Open access Sep 2026

TRIM21 blocks DDX3X-driven stress granule formation during Mycobacterium tuberculosis infection via a non-canonical E3 ligase mechanism

The analysis of human TB transcriptomic datasets showed that TRIM21 expression levels correlate with TB progression in human patients and demonstrated that TRIM21 deficiency suppresses Mtb growth in both macrophages and a murine model of tuberculosis (TB).

Rui-Yao Xu, Meng-Ru Lu, Gao-Yan Wang et al. · 0 citations

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