Open access
Sep 2026
NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication
This work establishes that NS1 coopts PARP1 phase separation via the HD rheostat to prolong transcriptional pausing, introducing ‘phase transition correction’ as an antiviral paradigm.
Shu-Feng Ma, Chang-Yuan Kang, Xi-Xian Liu et al.
· Advancement of science · 0 citations