Serum uric acid (SUA), the end product of purine metabolism, has opposing biological effects: it acts as an antioxidant at physiological concentrations but contributes to inflammation and endothelial dysfunction at elevated concentrations. Whether these effects translate into a concentration-dependent association w...
Zong-Jun Hu, Ya-Ping Su, Xia Huang· Scientific Reports· 0 citations
Background High triglyceride-glucose (TyG) index levels are linked to poor prognosis in the heart failure (HF) population. However, existing studies have predominantly relied on static baseline measurements, and the association of dynamic TyG trajectories with outcomes in critically ill HF patients remains unclear. Thi...
Zong-Jun Hu, Xiang-Ju Kong, Quan-Wei Liu et al.· Frontiers in Cardiovascular...· 0 citations
Mycoplasma pneumoniae pneumonia (MPP) can cause serious extrapulmonary complications, including life-threatening thrombosis. This study aimed to elucidate the roles of neutrophils and neutrophil extracellular traps (NETs) in vascular endothelial cell (EC) activation in pediatric MPP-associated thrombosis. We analyzed t...