Author

Xia Li

2 papers indexed here

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Open access Aug 2026

Dysregulation of local inhibitory inputs onto laterodorsal tegmental nucleus cholinergic neurons drives depression-like behaviors in mice.

Central cholinergic system plays a vital role in the pathogenesis of major depressive disorder. The cholinergic neurons in laterodorsal tegmental nucleus (LDTg) are the key components of the cholinergic system in brainstem. However, how the LDTg cholinergic neuronal activities are modulated in response to chronic stres...

Ya-Ling Xu, Jun Du, Xia Li et al. · Molecular Psychiatry · 0 citations

Open access Jul 2026

NAcLat-DBS reduces GABAB expression of dopamine neurons to correct depressive symptoms in CMS mice

Findings identify a previously unrecognized role of GABAB in mediating the antidepressant outcome of NAcLat-DBS and suggest that modulation of the DA GABAB1 in VTA-NAcLat pathway could represent a pharmacological target for treatment-resistant depression.

Jia-Ni Jing, Chao Yuan, Xia Li et al. · Neurotherapeutics · 1 citation