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Author

Xia Li

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Review Open access Sep 2026

Damage-associated molecular patterns in skeletal muscle: a double-edged sword - from sterile inflammation initiation to precision targeted therapeutic strategies.

Overall, DAMP-directed intervention in skeletal muscle will likely require selective and context-dependent modulation that limits pathological inflammation while preserving physiological repair and regeneration.

Zi-Hui Gao, Xia Li, Ya-Nan Ji et al. · 0 citations
Review Aug 2026

The neuroendocrine network imbalance in post-traumatic stress disorder: from core mechanisms to clinical translation.

How neuroendocrine alterations drive downstream molecular mechanisms-specifically neuroinflammation, a shift in the kynurenine pathway, mitochondrial dysfunction, and impaired brain-derived neurotrophic factor (BDNF) signaling-that collectively remodel stress-related brain circuits are explored.

Xia Li, Yanbei Zhu, Ya-Nan Ji et al. · 2 citations
Review Open access Jul 2026

The cGAS–STING pathway in tumor immunity: dual roles, regulatory mechanisms, and precision therapeutic strategies

This review systematically elucidates the molecular activation mechanisms of the cGAS–STING pathway and its complex regulatory networks within tumors, with a particular focus on analyzing its dual functions—tumor immune surveillance versus tumor promotion—and the determining factors involved.

Haiyan Jiang, Zhanzhan Li, Xia Li et al. · 2 citations
Review Jul 2026

The central role of endoplasmic reticulum stress in Parkinson's disease and targeted therapeutic strategies.

This review systematically elaborates on the key pathological roles and molecular mechanisms of ERS and the triggered UPR in Parkinson's disease and discusses various intervention approaches, their research progress, and associated challenges.

Xin Chen, Zihao Zhao, Xinlei Yao et al. · 6 citations

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