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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xia-Wei Liu

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Open access Jul 2026

Pathways to schizophrenia: Divergent effects of childhood trauma and polygenic risk on cognition and subcortical dynamics

Abstract Background Schizophrenia is often a persistent mental illness characterized by cognitive deficits and altered brain network dynamics especially affecting the cortico-subcortical salience processing system. Childhood trauma has been implicated in mechanisms contributing to schizophrenia, but the role of genetic...

Dan-Qing Huang, Yi-Cheng Long, Zhening Liu et al. · 0 citations
Aug 2026

Divergent cortical-subcortical intrinsic neural timescales in first-episode drug-naïve or minimally treated schizophrenia.

The findings show that first-episode drug-naïve or minimally treated schizophrenia patients are characterized by disrupted intrinsic neural timescales with distinct cortical-subcortical alterations, which may represent a candidate neurobiological marker of early-stage schizophrenia.

Xia-Wei Liu, Fei-Wen Wang, Yi-Ju Wang et al. · 0 citations

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