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Xian-Ding Sun

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Open access Sep 2026

pH-responsive Zn2+-coordinated gellan gum/γ-polyglutamic acid hydrogel microspheres as functional biomaterials for intra-articular delivery: physicochemical design, smart release, and chondroprotective performance in osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive degradation of the articular cartilage matrix, pain-related functional impairment, and a paucity of effective disease-modifying therapies. Curculigoside (Cur), a bioactive compound isolated from Curculigo orchioides, possesses anti-inf...

Kai-Ming Zhang, Hao-Nan Xue, Xiang-Wei Li et al. · 0 citations
Open access Aug 2026

Genome-wide association study of sarcopenia index reveals sex-stratified genetic architecture

The sarcopenia index (SI), defined as the ratio of serum creatinine to cystatin C, is a proposed biomarker of muscle mass and sarcopenia, yet its genomic basis and genetic architecture remain largely unexplored. We performed combined-sex and sex-stratified genome-wide association studies of SI in the UK Biobank. We exa...

Yu-Meng Mu, Bin-Zhi Liao, Meng-Liang Luo et al. · 0 citations

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