Although preclinical studies have validated ASF1A as a promising prognostic biomarker and therapeutic target, relevant clinical trials supporting its clinical application remain absent.
Jun Yin, Xiao-Jian Zhuo, Li-Hui Wen et al.· Experimental and Therapeutic...· 0 citations
This review systematically summarizes the molecular characteristics, physiological functions, disease regulatory networks, and current clinical translational status of OTUD1 with the aim of clarifying the molecular basis of its functional duality and providing a theoretical foundation for optimizing precision diagnosti...
Qing-Song Wang, Lijuan Zhang, Hong-Mei Cao et al.· Frontiers in Immunology· 0 citations
A review of the molecular characteristics and physiological functions of USP28, its context-dependent roles in neoplastic diseases, and its translational implications for targeted therapy and biomarker discovery highlights its potential as a therapeutic target for precision medicine.
Tong-Yong Luo, Shuncai Wu, Qing-Song Wang et al.· Frontiers in Immunology· 1 citation
The molecular characteristics and pathological mechanisms of RBM47 are summarized, the preclinical rationale for its potential utility as a biomarker and therapeutic node is discussed, and current research limitations, conflicting evidence, and translational bottlenecks are critically analyzed.
Shihua Huang, Qingsong Wang, Junhong Shen et al.· Frontiers in Immunology· 0 citations
The molecular regulatory networks of CELF4 and its mechanisms across multisystem diseases are reviewed, the current status and limitations of clinical translation are discussed, and future research on diagnostic biomarkers and therapeutic strategies targeting this protein is guided.
Qingsong Wang, Wenlong Yue, D. Lin et al.· Frontiers in Molecular Biosc...· 0 citations
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