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Xian-Wu Chen

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Open access Aug 2026

Industrial phenolic compounds targeting 11β-hydroxysteroid dehydrogenase 2: A comparative in silico and structure-activity investigation in humans and rats.

Industrial phenolic compounds (IPCs) are widespread environmental contaminants with known endocrine-disrupting potential. This study aimed to investigate the inhibition of 13 IPCs on human and rat 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2), a crucial enzyme responsible for cortisol inactivation. The inhibitory poten...

Lu-Bin Xie, Lei Shi, Yun-Bing Tang et al. · 0 citations

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