Pedunculoside alleviates cheilitis-like inflammation by suppressing the TLR3/TRIF/NF-κB signaling.
BACKGROUND Cheilitis is a lip-specific inflammatory disorder lacking safe long-term therapies. Topical glucocorticoids are limited by adverse effects, highlighting the need for plant-derived immunomodulators with dual anti-inflammatory and barrier-repairing effects. OBJECTIVE To evaluate the therapeutic potential, me...