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Xian-Yong Lan

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Open access Sep 2026

Ligand Fishing for Xanthine Oxidase Inhibitors From Brassica rapa L. via Bioaffinity Ultrafiltration‐HPLC‐MS/MS: Mechanistic Insights and In Vitro Anti‐Hyperuricemic Activity

Hyperuricemia is a prevalent metabolic disorder arising from dysregulated purine metabolism, wherein xanthine oxidase (XOD) serves as the key rate‑limiting enzyme catalyzing the final oxidation of hypoxanthine and xanthine to uric acid. Although Brassica rapa L. (chamagu) has been previously reported to exert ant...

Xuan-Bo Chen, Hai-Yu Wu, Zi-Wei Guo et al. · 0 citations
Open access Aug 2026

A Functional SNP Variant of the 3′ UTR Within the ELF5 Gene Affects Lactation Traits Through bta-miR-487a-Mediated Regulation in Holstein Dairy Cattle

The genetic and physiological variations among individuals of Holstein dairy cattle contribute to variations in milk yield. Selecting high-yield cows is critical for improving lactation performance. The present study aimed to identify functional genetic variants of the 3′ untranslated region (3′ UTR) in the ELF5 gene a...

Lin Ma, Li Sun, Haotian Zhang et al. · 0 citations

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