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Xianfei Shang

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Open access Jan 2026

Adaptive Evolution of Serotype O Foot‐and‐Mouth Disease Virus Under Vaccine Pressure: Combined VP1 T142/Q153 Mutations Drive Antigenic Alteration and Immune Evasion

Combined mutations at VP1 142 and 153 reshape viral antigenicity and act as core drivers of FMDV immune evasion, offering an experimental basis for clarifying FMDV evolution and developing broad‐spectrum vaccines.

Nan Cao, Ya-Mei Li, Xing-Hua Chen et al. · 0 citations
Jul 2026

Multi-copy expression of classical swine fever virus E2 in a recombinant pseudorabies virus enhances immunogenicity and supports its potential as a PRV-CSFV bivalent vaccine candidate.

It is suggested that multi-copy E2 expression enhances E2-associated immunogenicity and supports further optimization and evaluation of PRV-3CE2 as a PRV-CSFV bivalent vaccine candidate.

Xianfei Shang, Hui Zhao, Yufeng He et al. · 0 citations

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