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Author

Xianfeng Zhang

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Open access Sep 2026

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral...

Rui Luo, Jing Zhang, Ruojia Huang et al. · 0 citations
Open access Aug 2026

Protective monoclonal antibody targeting mycobacterial HBHA blocks the interaction with the novel attachment co-receptor NRP1 to inhibit Mycobacterium bovis entry.

INTRODUCTION The immune protection conferred by Bacillus Calmette-Guérin (BCG) is insufficient, underscoring the urgent need for novel strategies to control tuberculosis (TB). Although antibody-mediated responses targeting mycobacterial cell wall antigens have been observed during infection, the precise mechanism by wh...

Mengjin Qu, Xiang-Mei Zhou, Xianfeng Zhang et al. · 0 citations

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