GPER1: A Hidden Key in Cardio-Renal Axis-Unveiling its Therapeutic Potential for Heart and Kidney Disease.
Cardiovascular and kidney diseases are tightly interconnected through a bidirectional cardio-renal axis and exhibit pronounced sex-specific differences, implicating estrogen-associated signaling networks as critical modulators of disease susceptibility and progression. Among these, G protein-coupled estrogen receptor 1...