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Author

Xiang Gao

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2 papers indexed here

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Open access Sep 2026

HMGCS2-mediated ketogenesis maintains intestinal barrier in inflammatory bowel disease by inhibiting ferroptosis

Complete mucosal healing is a key therapeutic goal in inflammatory bowel disease (IBD). While ferroptosis-mediated epithelial cell death is known to compromise the mucosal barrier as the cornerstone of mucosal healing, the precise mechanisms driving this process during IBD pathogenesis remain to be fully elucidated...

Jing Han, Xiao-Ling Li, Ying Wang et al. · 0 citations
Open access Aug 2026

Efficacy and safety of upadacitinib for Crohn's disease in patients in East Asia: a post hoc analysis of randomized phase 3 studies.

BACKGROUND Upadacitinib is an oral Janus kinase inhibitor approved for the treatment of moderate-to-severe Crohn's disease (CD). This post hoc analysis reports the efficacy and safety of upadacitinib for CD in patients in East Asia enrolled in the phase 3 clinical trials. METHODS In two induction studies (U-EXCEL [NC...

Min-Hu Chen, Xiang Gao, Kenji Watanabe et al. · 0 citations

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