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Xiang-Guo Liu

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Open access Sep 2026

Tmem216 deficiency induces hydrocephalus via impaired ciliogenesis and disrupted ependymal planar polarity in mice.

It is demonstrated that central nervous system-specific inactivation of Tmem216 results in severe postnatal hydrocephalus and is identified as a critical TZ protein essential for ciliogenesis during ependymal development and establishing ependymal planar cell polarity.

Qian-Qian Gong, Zhuo-Wen Lv, Zhi-Lin Dou et al. · 0 citations

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