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Author

Xiangjie Kong

2 papers indexed here

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Open access Oct 2026

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Findings reveal that MD‐1 promotes pro‐inflammatory (M1‐like) macrophage polarisation in atherosclerosis by inhibiting NLRP3 inflammasome activation via a cGAS‐STING dependent pathway and suggest that MD‐1 neutralisation could be a potential therapeutic strategy for atherosclerosis management.

Fang Zhao, Zhi-Li Jin, Zhi-Wei Cai et al. · 0 citations
Open access Aug 2026

PLCE1 exacerbates the development of atherosclerosis by driving endothelial dysfunction and macrophage inflammation via targeting CTNNB1

Findings indicate that PLCE1 is an important regulator of vascular endothelial dysfunction, leading to a classical macrophage polarization switch through its interaction with CTNNB1, which collectively accelerates the development of atherosclerosis.

Wen-Lin Cheng, Yu-Fang Shi, Quan Zhang et al. · 0 citations

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