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Xiang-Jun Peng

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Open access Sep 2026

A designable twist-densification route to bioactive collagen hydrogel yarns approaching tendon-like mechanics

Reconstituted collagen hydrogels offer the bioactivity that load-bearing tissue engineering requires, but their Pascal to low-kPa moduli have confined them to non-structural roles, and the synthetic and hybrid strategies that close the mechanical gap typically forfeit that bioactivity. We show that a twist-induced dens...

Yang Xie, Wen-Jie Wu, Wei-Wei Zhang et al. · 1 citation
Review Jul 2026

Mechanosensitive ion channels in immunity from biophysics to mechanomedicine.

This view positions MSICs as translational substrates for next-generation immunotherapies in cancer, autoimmunity, fibrosis, and chronic inflammation, and connects this biology to the emerging mechanomedicine toolkit: sonogenetics, magnetogenetics, force-responsive nanoparticles, organ-on-chip platforms, and engineered...

Hangyu Zhang, Dexiang Jiang, Yi-Ming Mou et al. · 0 citations

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