Reconstituted collagen hydrogels offer the bioactivity that load-bearing tissue engineering requires, but their Pascal to low-kPa moduli have confined them to non-structural roles, and the synthetic and hybrid strategies that close the mechanical gap typically forfeit that bioactivity. We show that a twist-induced dens...
Yang Xie, Wen-Jie Wu, Wei-Wei Zhang et al.· Bioactive Materials· 1 citation
This view positions MSICs as translational substrates for next-generation immunotherapies in cancer, autoimmunity, fibrosis, and chronic inflammation, and connects this biology to the emerging mechanomedicine toolkit: sonogenetics, magnetogenetics, force-responsive nanoparticles, organ-on-chip platforms, and engineered...