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Open access Aug 2026

Clinical features associated with cerebrospinal fluid Epstein–Barr virus positivity in autoimmune GFAP astrocytopathy: a multicenter retrospective cohort study

Background Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an inflammatory disorder of the central nervous system. The clinical implications of Epstein–Barr virus (EBV) sequences detected in cerebrospinal fluid (CSF) by metagenomic next-generation sequencing (mNGS) remain uncertain. Methods This m...

Xing-Long Mao, Qian-Qian Qu, Chao Quan et al. · 0 citations
Sep 2026

Comparative effectiveness of inebilizumab versus conventional immunotherapies in AQP4-IgG-positive NMOSD: a prospective cohort study with time-varying treatment effects.

BACKGROUND To compare relapse and disability outcomes of inebilizumab, azathioprine (AZA), mycophenolate mofetil (MMF) and rituximab (RTX) in maintenance-therapy-naive patients with aquaporin-4 IgG-positive neuromyelitis optica spectrum disorder. METHODS We prospectively enrolled 566 patients (inebilizumab n=72, AZA...

Wenjuan Huang, Xin-Tong Zhang, Zhou-Zhou Wang et al. · 0 citations

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