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Open access Sep 2026

The deubiquitinating enzyme USP42 promotes lung adenocarcinoma progression through PTGS2

The ubiquitin-specific peptidase 42 (USP42) is a cysteine-dependent deubiquitinase with pro-tumorigenic roles in several cancers. In lung adenocarcinoma (LUAD), elevated USP42 expression correlates with advanced stage and poor survival, mirroring the prognostic impact of prostaglandin-endoperoxide synthase 2 (PTGS2) ov...

Hai-Nan Ye, Ji Shen, Dan Liu et al. · 0 citations

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