Author

Xiang-Ming Fang

2 papers indexed here

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Open access Sep 2026

Medial Prefrontal Cortex Modulation of the Peripheral Immune Response in Sepsis Via the Autonomic Nervous System.

BACKGROUND Sepsis is a life-threatening organ dysfunction syndrome caused by a dysregulated host response to infection, in which neuroimmune dysfunction plays a central role. The medial prefrontal cortex (mPFC) is involved in autonomic and immune regulation. However, its role in modulating peripheral immune responses d...

Wei-Yan Zhang, Qian Zhai, Xia-Wei Hu et al. · Anesthesia and Analgesia · 0 citations

Open access Sep 2026

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

ABSTRACT Sepsis‐induced acute lung injury (ALI) is a lethal inflammatory condition with limited therapeutic options. Macrophage autophagic homeostasis is essential to constrain septic ALI inflammation, though its upstream regulation remains elusive. Here, we report that lysosomal‐associated protein transmembrane 5 (LAP...

Lang Jiang, Qi-Lan Li, Hao Liu et al. · Advancement of science · 0 citations