Author

Xiang-Sheng Xiong

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Open access Sep 2026

Effective Dose 90 of Programmed Intermittent Epidural Bolus Volume at Three Ropivacaine Concentrations with Dural Puncture Epidural for Labor Analgesia: A Randomized Sequential Allocation Study

Background This study aimed to explore the ED90 of programmed intermittent epidural bolus (PIEB) volume for labor analgesia with different concentrations of ropivacaine when combining with dural puncture epidural (DPE) techniques. Methods Ninety patients were randomized to three groups (n=30 each) to receive an initial...

Lin-Sen Sun, Xiao-Juan Ding, Peng Zhai et al. · Drug Design, Development and... · 0 citations

Open access Aug 2026

Observational study on the application of different esketamine gargle doses for the prevention of postoperative sore throat after laryngeal mask airway insertion

Background Ketamine gargle is considered a highly effective measure for preventing postoperative sore throat (POST). This randomized controlled study aimed to explore the efficacy, safety, and optimal dosage of esketamine gargle for preventing POST following laryngeal mask airway insertion. Methods A total of 150 patie...

Le Bo, Yi Chen, Lin-Sen Sun et al. · Frontiers in Pharmacology · 0 citations