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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiang-Shu Xiao

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Open access Sep 2026

Protein Age Bias in Target Degradation by PROTACs.

The findings reveal that PROTAC-mediated degradation is governed not only by target engagement and ternary complex formation but also by the dynamic balance between protein synthesis and degradation, providing a mechanistic framework for incomplete degradation and rebound kinetics.

Bing-Bing X. Li, Xiang-Shu Xiao · 0 citations

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